The CCI 45acp shotshells cycle Glock 21's reliably. I've tested with a shotshell first, followed by a regular 230 gr. round and with a 230gr. round first, followed by a shotshell. Also with all shotshells. Cycles all without any issues. Recently dispatched a 3 ft. copperhead at about 7 feet. With 120 grains of #9 shot it did it's job well.
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CCI .45 AUTO shot shells
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