New Covid strain coming, mutated 32 times, possible resistant to any vaccine

[Featureless]

They're already using this to push the booster, and trying to change the definition of fully-vaccinated to mean 2 jabs AND a booster.

I got Covid is September, right around the time I was eligible for a booster. I already got the 2 jabs and from this point on no more jabs for me, no boosters, etc. There's studies out there that show those that were naturally infected have the best immunity, followed by those that were vaccinated then had a "breakthrough" infection like I got. The way I see it, my immune system is good right now, no need to get jabbed again. With any other booster they would draw titers first to see if you are still immune. None of this random boosters without first checking your immunity.

^^^^
I think Vinnie is a healthcare professional. IOW, active in interacting with actual hospital patients on a daily basis. The takeaway here is, just getting a series of 'vaccinations' when .gov and MSM tell you, should not be your first choice.

[stix213]

Wait, so they are OK calling this the Botswana strain, but calling it the Wuhan virus is racist????

Because China makes the rules, and doesn't like black people.

[stix213]

An article in Nature predicted back in January:

https://www.nature.com/articles/s41577-020-00493-9

An important point to reflect on is that the global vaccination programme against SARS-CoV-2 will generate pressure for antigenic escape variants. This has been observed for mucosal CoVs, where antigenic drifts located in spike protein diminish vaccine effectiveness9. Intermediate host adaptations may further contribute to the emergence of such variants. This is not a worrying development. A general principle of antigen recognition is that our immune system recognizes multiple different segments of a pathogen. This provides non-overlapping immune protection, already reported for SARS-CoV-2. In contrast to influenza viruses where there is extensive potential of new combinations, only limited changes in the spike protein of CoVs result in the generation of serotype variants.

The vaccines are against a single protein. Natural immunity is against all the parts of the virus. When you get 32 mutations in the spike protein, it still won't evade Natural immunity. You'd need significant mutations across all parts of the virus.

[elSquid]

The vaccines are against a single protein. Natural immunity is against all the parts of the virus. When you get 32 mutations in the spike protein, it still won't evade Natural immunity. You'd need significant mutations across all parts of the virus.

When a vaccinated person is infected for real their immune system will eventually be targeting various epitopes on the whole virus ( though the initial response would be looking for the epitopes seen on the spike protein created by the vax ), no reason to believe that it would be restricted. Why would it?

Another point: there are currently four circulating HCovs ( that are responsible for some of the common colds ) and "natural immunity" certainly hasn't wiped them out.

-- Michael

[The Gleam]

If scare is like a year and half ago, toilet paper, paper towels, cheap 3M N95 masks, isopropyl alcohol, coffee, and hand sanitizer may be in short supply soon. Stocking a few staples while prices are normal may be wise.

I know, right? I rushed out today to stock up on picture frames and dinner table place-mats.

---

[Deadon]

Some good laughs from over at you know where...


"I've gotten Pfizer so far, but I think for my next booster, I'll get a Moderna."

"I got the moderna booster because I initially got the J&J. Quick question: my kids got Pfizer. Can they get a moderna booster? Or, is it only J&J that can mix and match?"

Lol I read that same topic. Some crazy stuff. Kids can't even get boosters.

[foxtrotuniformlima]

The vaccines are against a single protein. Natural immunity is against all the parts of the virus. When you get 32 mutations in the spike protein, it still won't evade Natural immunity. You'd need significant mutations across all parts of the virus.

Remind us again where your PhD in virology is from......

[OleCuss]

They're already using this to push the booster, and trying to change the definition of fully-vaccinated to mean 2 jabs AND a booster.

I got Covid is September, right around the time I was eligible for a booster. I already got the 2 jabs and from this point on no more jabs for me, no boosters, etc. There's studies out there that show those that were naturally infected have the best immunity, followed by those that were vaccinated then had a "breakthrough" infection like I got. The way I see it, my immune system is good right now, no need to get jabbed again. With any other booster they would draw titers first to see if you are still immune. None of this random boosters without first checking your immunity.

My take on things is a bit different in some respects. And yeah, a lot of the following isn't really in response to you.

When Pfizer and Moderna came out with 3 week and 4 week intervals for immunization it appears that the intent was probably in to rapidly build immunity in the form of antibodies rather than to get the best immunity. Very early on there was a suggestion that the interval should probably be longer with a suggestion of 8 weeks advanced at the time.

There really aren't many vaccines I can think of where the interval specified for the first two doses is less than one month. That's because that is seldom an optimal dosing interval for building good cellular immunity.

It was pretty adequately shown that for some people with suppressed immune systems the immunity was really quite poor from just two doses at the currently recommended interval and a 3rd dose was recommended and not called a booster by those who were really tracking it closely.

It is common parlance to refer to the 3rd dose for most of us as a booster and I think the regulatory agencies and pharmaceutical companies will refer to it that way as well.

I think, however, that it might be reasonable to think of the third jab as completing the initial series. One might remember that children get a pretty long series of DTaP immunizations and it is also recommended that adults get the TDaP and then the Td or TDaP every 5-10 years (some questions as to whether that lifelong tetanus immunization recommendation is a good one).

We really don't have a standardized way of assessing the immunity from having a Covid-19 infection. It may make sense that mild cases result in less immunity than do severe cases but even that really isn't clear at this time.

Anyway, I've yet to get the third jab. I really am not sure I will as I suspect I've likely had the Covid-19 infection as I've had multiple exposures. Last month I didn't get tested but had symptoms which were certainly not classic for Covid-19 but were also not inconsistent and I ended up pretty much isolated for 10 days.

There's effectively no chance I'm going to get the third jab before January and if I do go for it I will be trying to get a different vaccine than I got in my first series. It seems likely to me that getting a different vaccine as the third jab would likely result in better coverage for the variants.

Anyway, I think everyone should be encouraged to study and make their own choices.

One other thing? One might note that the idea of a yearly booster is being embraced by Pfizer/Moderna/etc. but there is some serious thinking by Infectious Disease types that a yearly booster may not be needed/helpful. The FDA seems to be pushing things much faster/farther than a bunch of serious experts think is necessarily warranted.

The new FJB variant is not a reason for people to be changing their minds at this time. We don't have good information about its behavior.

[tomrkba]

There is no variant.

[OleCuss]

The vaccines are against a single protein. Natural immunity is against all the parts of the virus. When you get 32 mutations in the spike protein, it still won't evade Natural immunity. You'd need significant mutations across all parts of the virus.

There really isn't any good evidence to support that assertion.

And there are plenty of people who have had Covid-19 infections twice. Covid-19 infections don't induce perfect immunity and neither do the vaccines.

I'm pretty sure there is no good data which shows that the "natural immunity" will prevent people from getting the FJB variant or having reduced illness. The numbers I'm getting mean that there just really isn't enough data to get a sense of the pathogenic characteristics of this variant.

[Deadon]

My take on things is a bit different in some respects. And yeah, a lot of the following isn't really in response to you.

When Pfizer and Moderna came out with 3 week and 4 week intervals for immunization it appears that the intent was probably in to rapidly build immunity in the form of antibodies rather than to get the best immunity. Very early on there was a suggestion that the interval should probably be longer with a suggestion of 8 weeks advanced at the time.

There really aren't many vaccines I can think of where the interval specified for the first two doses is less than one month. That's because that is seldom an optimal dosing interval for building good cellular immunity.

It was pretty adequately shown that for some people with suppressed immune systems the immunity was really quite poor from just two doses at the currently recommended interval and a 3rd dose was recommended and not called a booster by those who were really tracking it closely.

It is common parlance to refer to the 3rd dose for most of us as a booster and I think the regulatory agencies and pharmaceutical companies will refer to it that way as well.

I think, however, that it might be reasonable to think of the third jab as completing the initial series. One might remember that children get a pretty long series of DTaP immunizations and it is also recommended that adults get the TDaP and then the Td or TDaP every 5-10 years (some questions as to whether that lifelong tetanus immunization recommendation is a good one).

We really don't have a standardized way of assessing the immunity from having a Covid-19 infection. It may make sense that mild cases result in less immunity than do severe cases but even that really isn't clear at this time.

Anyway, I've yet to get the third jab. I really am not sure I will as I suspect I've likely had the Covid-19 infection as I've had multiple exposures. Last month I didn't get tested but had symptoms which were certainly not classic for Covid-19 but were also not inconsistent and I ended up pretty much isolated for 10 days.

There's effectively no chance I'm going to get the third jab before January and if I do go for it I will be trying to get a different vaccine than I got in my first series. It seems likely to me that getting a different vaccine as the third jab would likely result in better coverage for the variants.

Anyway, I think everyone should be encouraged to study and make their own choices.

One other thing? One might note that the idea of a yearly booster is being embraced by Pfizer/Moderna/etc. but there is some serious thinking by Infectious Disease types that a yearly booster may not be needed/helpful. The FDA seems to be pushing things much faster/farther than a bunch of serious experts think is necessarily warranted.

The new FJB variant is not a reason for people to be changing their minds at this time. We don't have good information about its behavior.

I'm pretty sure Israel is on the 4 BOOSTER. Or do you think that's part of the routine?

[Deadon]

There is no variant.

Honestly that's my thoughts. They said the Vax didn't work well with delta. Then this comes out and it's "we'll whip up a new Vax in 100 days to fit the new mutation." So the question no one is answering is why didn't they do this for delta? My GUESS is maybe from all the sheep they got a good trial and this new vaccine might just work now. No way they can tell the public this so they say it's mutated but don't worry we have a new vaccine.

If this isn't the reason then why not replace the alpha vaccine when delta happened to stop the spread back then?

[Caligula36]

[turbolxstang]

I'm scared for my children, this might be a good time to get them the vax

[glilon]

A variant that is unaffected by vaccines is just what they want. We can be deathly afraid of it until it reaches its peak in Nov. of next year. Lockdowns will allow mail-in voting only.