Basic lesson in Immunity, media doesn’t know ****. Covid-19.

[boris badinov]

It doesn't need to, your body will stop producing antibodies in a matter of weeks to months if it responds to SARS-CoV2 like it does every other species of coronavirus.

You can catch exactly the same strain of common cold coronaviruses multiple times a year.

^this

All around the world their are growing pockets of "recovered" covid patients who've tested negative for the virus and positive for antibodies who are once again testing positive for the virus.

Its absolutely false that antibodies have the same effectiveness for every contagion that enters the body.

[sakosf]

^this

All around the world their are growing pockets of "recovered" covid patients who've tested negative for the virus and positive for antibodies who are once again testing positive for the virus.

Its absolutely false that antibodies have the same effectiveness for every contagion that enters the body.

I have read that myself. I think the unanswered this though, is these individuals who recovered, actually clear the virus from their body or was the virus able to evade the immune system and then reemerge once the immune response subsided.....?

[capo]

I have read that myself. I think the unanswered this though, is these individuals who recovered, actually clear the virus from their body or was the virus able to evade the immune system and then reemerge once the immune response subsided.....?

Agreed, this virus seems very stubbornly entrenched in a small subset of cases. Those results are still anecdotal at this time even though the evidence is certainly mounting, no clear studies have been done to establish whether these rare cases are clear evidence of re-infection or some degree of a latent one, though not through the traditional means.

It seems a serious complication for this disease is an improper immune response to infection. It appears not exceedingly rare for more severe cases to have either over-reactive or under-reactive immune mobilization and response which lead to a variety of potential complications, one being a seeming inability to completely clear the virus from one's system.

[cleonard]

Agreed, this virus seems very stubbornly entrenched in a small subset of cases. Those results are still anecdotal at this time even though the evidence is certainly mounting, no clear studies have been done to establish whether these rare cases are clear evidence of re-infection or some degree of a latent one, though not through the traditional means.



It seems a serious complication for this disease is an improper immune response to infection. It appears not exceedingly rare for more severe cases to have either over-reactive or under-reactive immune mobilization and response which lead to a variety of potential complications, one being a seeming inability to completely clear the virus from one's system.

From a lot of the reports, it is first a failed response and then an improper response that does them in. Many have an initial illness for five to seven days, a partial remission of symptoms and then the cytokine storm reaction leading to ARDS.

Several papers have talked about immune system fatigue.

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[capo]

I've been trying to find papers on this. I'd like to understand why there is no lasting immunity to Corona viruses. Do the memory cells behave differently than for measles? Is it the antigenic parts of the virus changing so the old immunity doesn't recognize the new version?

One future concern is that due to the memory cell that do exist, future infections may have a more severe cytokine storm. Bad juju for sure.

The amount we don't know is very large.



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I don't know of any human studies done able to define the exact nature of immune system memory for specific viral infections, also with this virus immune response seems to run the gamut so I wouldn't expect studying a small group of randomly chosen individuals would necessarily cover the entire spectrum.

I did however find this.

https://www.jimmunol.org/content/186/12/7264

For general coverage of the immune memory response for other readers, this.

https://www.frontiersin.org/articles/10.3389/fimmu.2019.01787/full

[Wherryj]

if you dont become immune you would never be over it because you would be instantly re-infecting yourself

Unfortunately there are infections where that pretty much happens. The immunity seems to be so short lived that the disease can be reacquired within a week of recovery. One would hope that having had it once means that the immune system may still at least have some cells circulating that could quickly be mobilized to fight the reinfection-sort of like how booster shots don't need the same amount of antigen exposure or time to get the effect-but you never know.

[compulsivegunbuyer]

It doesn't need to, your body will stop producing antibodies in a matter of weeks to months if it responds to SARS-CoV2 like it does every other species of coronavirus.

You can catch exactly the same strain of common cold coronaviruses multiple times a year.

Do you have a link to some peer reviewed research with this current virus that backs this up?

[CAL.BAR]

Yes, ignorant masses tend to accept & believe anyone who has many capital letters after their name. That's what impresses.

And the rest of the "ignorant masses" REFUSE to believe anyone with any letters after their name.

[Hoooper]

Do you have a link to some peer reviewed research with this current virus that backs this up?

The post you quoted says "if it responds to SARS-CoV2 like it does every other species of coronavirus". What kind of peer reviewed research with this virus would you expect to show an "if"?

[zhyla]

I saw something about some people who had tested positive then later showed no antibodies. Makes no sense.