Vaccine interaction with meds hypothetical musings...

[RANGER295]

I was having a discussion with a science teacher about different covid treatment options, vaccines, and some in general pointless nonsense. I brought up ivermectin which she thinks you would be bat poo crazy to take. We talked about how it may or may not work and I said I believed it had something to do with slowing down the replication of the virus.

She said if that was true it would lessen the effectiveness of the vaccine.

For the sake of argument assume that the vaccine is effective and ivermectin works. Would her statement hold any water???

[HibikiR]

No, antibodies and Ivermectin target different things (and that might be a good thing regarding synergy) and they have no overlap regarding metabolism (Ivermectin is metabolized by the liver so any other meds that interact with cytochrome P450 enzymes would be a concern)

[stonefly-2]

Yes,

ivermectin is an ace 2 inhibitor and spike proteins do their damage when they dock at ace receptors.

Basic high school biology, Ivermectin gets there first.

[HibikiR]

Think of it this way:

-Antibodies are like condoms that go on the spike protein.

-Ivermectin is like a chastity belt that go on the ACE2 receptor.

A condom and a chastity belt don't physically interfere with each other and therefore don't interfere so much as they synergize for increased "coverage".

[71MUSTY]

Think of it this way:

-Antibodies are like condoms that go on the spike protein.

-Ivermectin is like a chastity belt that go on the ACE2 receptor.

A condom and a chastity belt don't physically interfere with each other and therefore don't interfere so much as they synergize for increased "coverage".

WOW so scientific. Another well respected Doctor on the internet I presume.

[stonefly-2]

Think of it this way:

-Antibodies are like condoms that go on the spike protein.

-Ivermectin is like a chastity belt that go on the ACE2 receptor.

A condom and a chastity belt don't physically interfere with each other and therefore don't interfere so much as they synergize for increased "coverage".

Spike proteins "are" the antibodies,

are you saying the jab has anything whatever that interacts with the virus Sars cov 2 ?


Or just the spike proteins.....the stated objective
(giving the benefit of the doubt)
for which is to induce the body to generate it's own spike proteins to protect from the damaging ones created in the cytokine storm of the secondary stage of Covid.

Overlooking (again giving the benefit of the doubt) that a lipid capsule developed for it's ability to allow medication to slip the brain/ blood barrier also allows 40 billion of what the stated intent of the jab was intended to protect against flood the vascular system all at once rather than staying in the arm muscle and releasing gradually.

Kinda explains why the jab is not keeping people from getting or spreading Covid and killing them at the same time as the spike proteins find a weak spot doesn't it?
(no preexisting condition needed)


As applied to hypertension but is the mechanics not the same?

https://www.youtube.com/watch?v=xIlaQuRaZmk

[HibikiR]

Spike proteins "are" the antibodies,

are you saying the jab has anything whatever that interacts with the virus Sars cov 2 ?


Or just the spike proteins.....the stated objective
(giving the benefit of the doubt)
for which is to induce the body to generate it's own spike proteins to protect from the damaging ones created in the cytokine storm of the secondary stage of Covid.

Overlooking (again giving the benefit of the doubt) that a lipid capsule developed for it's ability to allow medication to slip the brain/ blood barrier also allows 40 billion of what the stated intent of the jab was intended to protect against flood the vascular system all at once rather than staying in the arm muscle and releasing gradually.

Kinda explains why the jab is not keeping people from getting or spreading Covid and killing them at the same time as the spike proteins find a weak spot doesn't it?
(no preexisting condition needed)


As applied to hypertension but is the mechanics not the same?

https://www.youtube.com/watch?v=xIlaQuRaZmk

Spike proteins are the antigens, which are taken up by APCs (i.e. dendritic cells) and expressed on their MHC-2 to naive CD4+ T-helper cells with the correct affinity to spike proteins. The T-helper cell is activated and begins to coordinate the body's adaptive response to the spike protein (and by extension the COVID-19 virus) and that includes activating the correct B-cell required to produce the IgM antibody for the spike protein. After about 2 weeks the B-cell with undergo all the changes to create better IgG antibodies for the spike protein and fully differentiate to the B-memory cell (long term protection) and the antibody factory that is the plasma cell.

Traditional vaccines (i.e. Novavaxx) contain the completed spike proteins manufactured using living cells (moth cells in the case of Novavaxx). mRNA vaccines (i.e. Pfizer) contain the instructions to manufacture spike proteins and use your body's cells instead of other living cells to manufacture the spike protein. The APCs will still present either of them.

WOW so scientific. Another well respected Doctor on the internet I presume.

You do know what an analogy is, right?

[stonefly-2]

Spike proteins are the antigens, which are taken up by APCs (i.e. dendritic cells) and expressed on their MHC-2 to naive CD4+ T-helper cells with the correct affinity to spike proteins. The T-helper cell is activated and begins to coordinate the body's adaptive response to the spike protein (and by extension the COVID-19 virus) and that includes activating the correct B-cell required to produce the IgM antibody for the spike protein. After about 2 weeks the B-cell with undergo all the changes to create better IgG antibodies for the spike protein and fully differentiate to the B-memory cell (long term protection) and the antibody factory that is the plasma cell.

Is that a yes or a no?

A polio vaccine introduces attenuated form of the polio virus to induce the body to develop antibodies that fight that virus.

Now polio is a rarity.

[HibikiR]

Is that a yes or a no?

A polio vaccine introduces attenuated form of the polio virus to induce the body to develop antibodies that fight that virus.

Now polio is a rarity.

The answer is there, if you can't see it that's a "you" problem. If you "misinterpret" it because of bias/grudge, that's also a "you" problem.

Regarding hypertension, are you confusing ACE (has no 2) with ACE2?

[stonefly-2]

The answer is there, if you can't see it that's a "you" problem. If you "misinterpret" it because of bias/grudge, that's also a "you" problem.

Regarding hypertension, are you confusing ACE (has no 2) with ACE2?

No need to get pissy....everyone plays the fool sometimes.

[HibikiR]

No need to get pissy....everyone plays the fool sometimes.

You are definitely the example I think of when it comes to "pissy" and "fool". A masterclass on both really.