Unconfigured Ad Widget

**sd_shooter** · 08-05-2021, 1:55 PM

That's why I'm not getting the shot

**stix213** · 08-05-2021, 1:58 PM

So with 9 months for natural immunity, it sounds like someone like me who believes they caught this right at the start before the first lockdowns or widespread testing was available, I'm probably vulnerable to having to take a few paid days off to recover from this again. Good to know.

Or was the 9 months in your last quote just the length of the study, with immunity lasting much longer?

**flyinbronco** · 08-05-2021, 3:42 PM

I'd like to know why the so called experts aren't talking about this. They're so busy pushing the jab but with the possibility of 100 million or more in the US having natural immunity is a game changer in herd immunity. It should be studied.

**sd_shooter** · 08-05-2021, 3:59 PM

Originally posted by flyinbronco

I'd like to know why the so called experts aren't talking about this. They're so busy pushing the jab but with the possibility of 100 million or more in the US having natural immunity is a game changer in herd immunity. It should be studied.

Tens of Trillions of dollars to be divided up between politicians and Big Pharma. Why on earth would any of them be motivated by something that is $0.00?

**mshill** · 08-05-2021, 4:01 PM

Originally posted by bangel

I wanted to share some research I've done over the last couple weeks on natural immunity. My questions were: does it exist, how good is it, does it compare to vaccine immunity, how long does it last. I think it's a shame that this information isn't being discussed by our public health officials nor by the news media.

My summary: Natural immunity provides broad, diverse immunity, with neutralizing antibodies more effective in neutralizing COVID than vaccine-induced, even against variants. Natural immunity provides long-lasting circulating memory B cells and humoral T cells - likely to last dozens of years similar to SARS-CoV-1 natural immunity.

Just a moment...

https://www.cell.com/cell-reports-medicine/fulltext/S2666-3791(21)00203-2

303 See Other

https://www.nature.com/articles/s41586-021-03647-4

SARS-CoV-2 variants of concern exhibit reduced sensitivity to live-virus neutralization in sera from CoronaVac vaccinees and naturally infected COVID-19 patients

https://www.medrxiv.org/content/10.1101/2021.07.10.21260232v2

Recent surges in SARS-CoV-2 variants of concern (VOCs) call for the need to evaluate levels of vaccine-and infection-induced SARS-CoV-2 neutralizing antibodies (NAbs). CoronaVac (Sinovac Biotech, Beijing, China) is currently being used for mass vaccination in Thailand as well as other low-income countries. Three VOCs currently circulating within Thailand include the B.1.1.7 (Alpha), B.1.351 (Beta), and B.1.617.2 (Delta) strains. We assessed NAb potency against the prototypic strain containing the original spike sequence (WT) compared to that against the 3 VOCs using sera derived from a cohort of healthcare workers who received a full 2-dose regimen of CoronaVac. Sera from two other cohorts consisting of COVID-19 patients who had been hospitalized in 2020 and 2021 were evaluated for comparison. We found that, despite equally robust production of S1-RBD-binding IgG and 100% seropositivity, sera from both CoronaVac vaccinees and naturally infected individuals had significantly reduced neutralizing capacity against all 3 VOCs compared to WT. Strikingly, NAb titers against Alpha and Beta were comparable, but Delta appears to be significantly more refractory to NAbs in all groups. Our results may help inform on CoronaVac NAb-inducing capacity, which is a proxy for vaccine efficacy, in the context of the WT strain and 3 VOCs. Our results also have critical implications for public health decision-makers who may need to maintain efficient mitigation strategies amid a potentially high risk for infection with VOCs even in those who have been previously infected. ### Competing Interest Statement The authors have declared no competing interest. ### Funding Statement This work was supported by the National Research Council of Thailand, the Mahidol University for Integrated and Multidisciplinary Research Cluster grant (MRC-IM 02/2564), the Program Management Unit C, and the Ramathibodi Foundation. Funding sources had no involvement in study design, data collection, analysis or interpretation, nor in the writing of the manuscript and in the decision to submit the manuscript for publication. ### Author Declarations I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained. Yes The details of the IRB/oversight body that provided approval or exemption for the research described are given below: All methods were performed following standard protocols approved by the institutional review committee. The study protocol and human ethics were approved by the Human Research Ethics Committee, Faculty of Medicine Ramathibodi Hospital (COA. MURA2021/264) and the Ethics Committee of National Cancer Institute, Thailand (EC COA 019/2021). All necessary patient/participant consent has been obtained and the appropriate institutional forms have been archived. Yes I understand that all clinical trials and any other prospective interventional studies must be registered with an ICMJE-approved registry, such as ClinicalTrials.gov. I confirm that any such study reported in the manuscript has been registered and the trial registration ID is provided (note: if posting a prospective study registered retrospectively, please provide a statement in the trial ID field explaining why the study was not registered in advance). Yes I have followed all appropriate research reporting guidelines and uploaded the relevant EQUATOR Network research reporting checklist(s) and other pertinent material as supplementary files, if applicable. Yes The data used to support the findings of this study are included within the article

https://www.biorxiv.org/content/10.1...581v1.full.pdf

OP, thanks for the links. This is what I have been looking for.

**numpty** · 08-05-2021, 4:35 PM

Originally posted by stix213

So with 9 months for natural immunity, it sounds like someone like me who believes they caught this right at the start before the first lockdowns or widespread testing was available, I'm probably vulnerable to having to take a few paid days off to recover from this again. Good to know.

Or was the 9 months in your last quote just the length of the study, with immunity lasting much longer?

I think my family got it in February/March of 2020 but we never confirmed because no one was testing at that point. We just thought it was the flu. I'm glad the doctors didn't know it was covid or we would have been put on ventilators and probably dead by now. No, they just treated it like the flu except I got a round of Prednisone and a Z-pak because my lungs were really clogged up and the albuterol breathing treatment didn't do anything.

All that being said, we got it again (this time confirmed) just a couple of weeks ago. This time was much more mild. I wouldn't have taken off of work if I didn't know it was Covid. My wife has a lingering cough/congestion which she typically doesn't get, but she's getting better too.

So I'd say it's probably like the flu in that you could get it and then be susceptible again the following year but not have much to worry about until the season comes around again.

**DaveInOroValley** · 08-05-2021, 5:02 PM

Saved those links, thanks OP.

**five.five-six** · 08-05-2021, 5:26 PM

There is absolutely no money in natural immunity.

You guys are a bunch of anti-VAX or conspiracy theorist.

**Dan_Eastvale** · 08-05-2021, 5:41 PM

I know more about the effectiveness of immune system significantly more than the government or the CDC does.

**bangel** · 08-06-2021, 9:40 AM

Originally posted by stix213

So with 9 months for natural immunity, it sounds like someone like me who believes they caught this right at the start before the first lockdowns or widespread testing was available, I'm probably vulnerable to having to take a few paid days off to recover from this again. Good to know.

Or was the 9 months in your last quote just the length of the study, with immunity lasting much longer?

The 9 months was the length of the study. I also found another study today that confirmed 11 months of immunity - testing confirmed memory B cells and humoral immunity.

Many of the studies say the implication is that long-term immunity could last many, many years, with comparisons to SARS-CoV-1 immunity being proven to last 12+ years.

**71MUSTY** · 08-06-2021, 9:48 AM

I am pretty sure my son and I had natural immunity. Had major exposure several times but tested negative for COVID and the antibodies each time. Whatever protected us was natural and not antibody driven.

Obviously nobody gets power from talking about the 30 to 50% of the population with natural immunity problem is there is no real way for an individual to test for it.

Logic says that would have been one of the first tests approved.

**Scota4570** · 08-06-2021, 9:52 AM

Natural immunity is not recognized. They would rather force a $10 shot on everyone. They know some will die for from the shot. They know that delta is not a real threat the the majority.

Now you know the value they place on your life, $10. ( Or, whatever the vax shot really costs)

**bangel** · 08-06-2021, 10:17 AM

Originally posted by 71MUSTY

I am pretty sure my son and I had natural immunity. Had major exposure several times but tested negative for COVID and the antibodies each time. Whatever protected us was natural and not antibody driven.

Obviously nobody gets power from talking about the 30 to 50% of the population with natural immunity problem is there is no real way for an individual to test for it.

Logic says that would have been one of the first tests approved.

We have had tests that can check for the spike RBD neutralizing antibodies. Those are the ones that fade away after some months.

The long lasting immunity studies can involve checking bone marrow for T-cells.

I'm going to look for a place that can do this test: https://www.t-detect.com/ they just got EUA approval a couple months ago from FDA.

Unconfigured Ad Widget

Natural Immunity Studies

Natural Immunity Studies

Comment

Comment

Comment

Comment

Comment

Comment

Comment

Comment

Comment

Comment

Comment

Comment

Comment

Calguns.net Statistics

What's Going On