Chloroquine or hydroxychloroquine are considered safe in all trimesters of pregnancy

[SAN compnerd]

Prophylactic use of antimalarials during pregnancy

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215604/

I understand it's pretty normal for some women in Africa to take this to prevent Malaria during pregnancy.

Kind of doesn't line up with the sensational headline by the WaPo about an Arizona man dying (from aquarium cleaner) or the piece out of Sidney that claims two died from this stuff after Trump mentioned it.

[Sierra57]

Nope. Chloroquine and hydroxychloroquine be BAD!!!! Maybe even more badderer than Orange Man.

I know this because the Dems say so.

[SAN compnerd]

Nope. Chloroquine and hydroxychloroquine be BAD!!!! Maybe even more badderer than Orange Man.

I know this because the Dems say so.

Ok comrade, I'll get the propaganda straight next time. Just don't tell Dear Leader, I don't want to go to 'quarantine'.

[cleonard]

Ok comrade, I'll get the propaganda straight next time. Just don't tell Dear Leader, I don't want to go to 'quarantine'.

Chloroquine has a low therapeutic index. An overdose can certainly kill you by stopping your heart.

[jglabe]

[Marthor]

Chloroquine is on the World Health Organization list of safe and essential medications.

[SAN compnerd]

Chloroquine has a low therapeutic index. An overdose can certainly kill you by stopping your heart.

And yet it's safe enough to give pregnant women at any stage of pregnancy.

Been around for 50 years, efficacy and safety are not at all in question with this drug, no matter how much the fake news tries to sensationalized this against Trump.

Is Gov Cuomo wrong for doing trials for this too? Or is it just Trump who is wrong?

[cleonard]

And yet it's safe enough to give pregnant women at any stage of pregnancy.

Been around for 50 years, efficacy and safety are not at all in question with this drug, no matter how much the fake news tries to sensationalized this against Trump.

Is Gov Cuomo wrong for doing trials for this too? Or is it just Trump who is wrong?

I think I may have cross posted. I was probably intending that for the Arizona idiot thread.

I'm with you on it's relative safety. The primary issue is a dose dependent elongation of the QT interval which can lead to fatal arrhythmia in an overdose situation or those predisposed. This is why it is a prescription med and available over the counter in the US. I hope that there is some available if I require some in the future. I'd take it without a second thought.

[SAN compnerd]

I think I may have cross posted. I was probably intending that for the Arizona idiot thread.

I'm with you on it's relative safety. The primary issue is a dose dependent elongation of the QT interval which can lead to fatal arrhythmia in an overdose situation or those predisposed. This is why it is a prescription med and available over the counter in the US. I hope that there is some available if I require some in the future. I'd take it without a second thought.

[Chewy65]

So you think the World Health Organization says that chloroquine is safe for treating pregnant women for malaria. Keep in mind the dosages used in China and South Korea to treat COVID-19 were 500 mg once or twice a day. Not 25 mg for treating pregnant women.

For WHO prescription information see https://apps.who.int/medicinedocs/en...22e/2.5.1.html

Adverse effects

Serious adverse effects are rare at the dosages used for malaria, but pruritus, which may be intolerable, is common among Africans and has also been reported from South and Central America and south-east Asia. It can often be alleviated by calamine lotion but if it compromises compliance it may be necessary to use an alternative antimalarial.

Transient headaches and gastrointestinal symptoms are occasionally troublesome. In susceptible individuals, severe attacks of acute intermittent porphyria and of psoriasis may be precipitated. The former may simulate an attack of cerebral malaria. When the diagnosis is in doubt the urine should be tested for porphobilinogen.

Where self-medication is common and chloroquine is used without supervision to treat virtually any febrile condition, chloroquine abuse has been claimed to be a common cause of cardiac atrio-ventricular block. These patients are also at risk of developing chloroquine retinopathy.

Irreversible visual impairment resulting from accumulation of chloroquine in the retina is a recognized complication of long-term, high-dosage therapy. Total lifetime exposure to chloroquine should not exceed 100g of the base. Retinopathy has rarely, if ever, resulted from doses currently recommended for malaria prophylaxis.

Overdosage

Acute chloroquine poisoning is often fatal: oral doses as low as 50 mg base/kg can be lethal. Nausea, vomiting and drowsiness occur rapidly and are followed by slurring of speech, agitation, breathlessness due to pulmonary oedema, convulsions, coma, impaired vision and cardiac dysrhythmias

[SAN compnerd]

So you think the World Health Organization says that chloroquine is safe for treating pregnant women for malaria. Keep in mind the dosages used in China and South Korea to treat COVID-19 were 500 mg once or twice a day. Not 25 mg for treating pregnant women.

For WHO prescription information see https://apps.who.int/medicinedocs/en...22e/2.5.1.html

The Chicoms own the WHO, and as such I don't trust anything they say at this point.

That's why I included a link to the info from the NIH.

All drugs have side effects and knowing what they are is just common sense.

Writing fake news stories about the dangers of a clearly safe drug is not needed at this time, but they are out there.

[Chewy65]

The Chicoms own the WHO, and as such I don't trust anything they say at this point.

That's why I included a link to the info from the NIH.

All drugs have side effects and knowing what they are is just common sense.

Writing fake news stories about the dangers of a clearly safe drug is not needed at this time, but they are out there.

What link? If you mean this one, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215604/ , the paper is from 2011 and I am not telling you to trust the WHO or China. Just the opposite, I am telling people not to rely too much on what they think the WHO says about it being save for pregnant woman. Even if they take it in very small doses, it has risks. Safety is relative, I suppose.

You talk about commons sense. As yourself if your argument makes any sense, when you say all drugs have side effects and in the next pen stroke you say that this one is perfectly safe.

Before determining to use any drug you have to consider its efficacy for a particular condition and balance the likelihood that it will successfully treat the condition against the likelihood of adverse effects and how serious those effects may impact the particular patient. Young with no known preexisting conditions but in serious need of intervention, use the drug where you may determine it is too dangerous to chance on a patient in a high risk group.

[capo]

Don't confuse prophylactic with therapeutic dosage, they are very different.

Also I don't believe there's any evidence yet suggesting prophylactic dosages of any form of chloroquine are effective at preventing this disease.

We're in the trial stages of evaluating medications for treating covid-19 and in the initial stages for identifying preventive medicines. Don't get ahead of the medical science and don't take anything without a doctor's prescription.

[SAN compnerd]

Don't confuse prophylactic with therapeutic dosage, they are very different.

Also I don't believe there's any evidence yet suggesting prophylactic dosages of any form of chloroquine are effective at preventing this disease.

We're in the trial stages of evaluating medications for treating covid-19 and in the initial stages for identifying preventive medicines. Don't get ahead of the medical science and don't take anything without a doctor's prescription.

Just an effort to mute the fake news that suddenly after Trump mentions this medication that suddenly people are being harmed by it.

It has a decades long track record of safety when taken correctly.

This Australian piece claims people died in Lagos from chloroquine overdose, but if you read the piece it does not say that at all.

https://www.smh.com.au/world/africa/coronavirus-takes-hold-in-africa-as-chloroquine-deaths-follow-trump-promotion-20200322-p54co9.html

[2shotjoe]

don't take the fish cleaner or anything without a doctor's prescription.