Most autoloading cartridges headspace on the crimp and can be used without moonclips. Ejection can be a problem with a swingout cylinder because, with a couple of exceptions, the ejector star cannot push the empties out. A SA ejects the empties normally.
Calibers designed for revolvers headspace on the rim. If you have a revolver set up correctly for mooclips in 38/357, it will work normally either way.
Calibers designed for revolvers headspace on the rim. If you have a revolver set up correctly for mooclips in 38/357, it will work normally either way.

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