I am also a fan of the GLOCK 29 in 10MM but since you said you're not a 'gun guy' and ammo for the 10 is expensive I would say get a GLOCK 30 in .45 ACP. (you mentioned .45 ACP already)
It is a lightweight piece (unlike a heavy metal 1911) and holds 9 rounds. Very accurate and soft shooting; ammo is available and not expensive.
It will handle any encounters you come across.
Both the Glock 29 in 10MM and the Glock 30 in .45 are the exact same frame and size.
I run 13 round preban mags in mine and an aftermarket lonewolf barrel so I can shoot my lead reloads. But if I were hiking I would just run it stock; good enough.