Lee hand press
I started with a Lee hand press and still use it for about 80% of my reloading. I usually measure powder by volume (Lee dippers) but you should have a scale to check the weights before and occasionally during your loading session.
I load 9mm, .38, .357, .44 spl, .44 mag, .45 ACP and .45 Colt on the press with carbide dies (LEE and RCBS).
I mostly load the .38 and .44 spl since these shoot rather well with cast bullets at modest velocities. If I'm off a little on the powder charge it doesn't seem to matter but MAKE SURE YOU DON'T DOUBLE CHARGE A CASE! Have a system/routine and double check.
I weigh each charge for the magnum loads and anything near plus P pressure. I use jacketed bullets for these and it's not hard to get good results but the cost goes up due to the bullets.
As far as overall cost, buy primers by the 1000 at 3-4 cents each. Powder is close to the same for mild loads. Price of the projectile is the main cost after your initial set up (press, dies etc).
It's worth it if:
A) you shoot a lot
B) you get enjoyment spending time reloading and finding different loads
I'd recommend you get some .38 and .44 spl brass and give it a try.
Let us know how it goes.