The problem with fast powders is that they generate full pressure without very much speed. Loaders then try to get standard or full speed loads by increasing the charge without knowing what they are doing. The first thing to let go in a Glock with an unsupported chamber is typically the part of the case that is unsupported.
An ignorant loader trying to get Power Pistol speeds using Red Dot will be capable of blowing up any gun.
You'll be ok so long as you don't exceed published loads and read your loading manuals.