Lately I've been recommending .22's to new shooters. Mostly M&P 15-22's, lcr's, sr22's and 10/22's for the following reasons.
1. Better than nothing
2. Low felt recoil especially for those with disabilities.
3. Ammo is cheap (or it was). Practice is important. New shooters need to shoot!! If they stick with it, they can always upgrade later.
4. Stingers and other high velocity ammo is available for defense if they really want. The Ruger LCR, 10/22, & SR22 seem reliable enough. The LCR has the edge for ease of cleaning and ability to quickly get past a dud round.
I don't think I've ever assisted in a shooting investigation with a .22. I can't add too much real world experience.